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0.14 s That is, 0.14 s will seem to pass on the ship as 1 s passes on Earth. The time dilation factor k in this case is 1/0.14, or approximately 7.1. Time flows more than seven times more slowly on a ship moving at 99 percent of the speed of light than it flows on Earth from the reference frame of someone on Earth. As you can imagine, this has implications for time travel. According to the special theory of relativity, if you could get into a space ship and travel

Regardless of which instrument is used, the temporal portion of the incision should extend only through skin so as to avoid dividing the terminal branch of the lacrimal artery, which passes between skin and orbicularis muscle at the level of the lateral orbital rim.8 Once the initial incision is complete, a toothed forceps is used to elevate the temporal end of the ellipse so that a skin ap may be dissected with the laser. This is performed easily if traction is kept on the

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the last being associated with secondary adrenal hyperplasia, the term Cushing syndrome is appropriate Some components of the syndrome may be lacking or less conspicuous than in orid Cushing disease; diagnosis is then facilitated by measurements of ACTH and cortisol in the blood and urine Cushing syndrome of ectopic type tends to differ clinically from primary pituitary Cushing disease with respect to its more rapid development and greater degrees of skin pigmentation, hypokalemia, hypertension, and glycosuria Plasma concentrations of ACTH exceed 50 mg/ dL in the ectopic type and are not suppressed by dexamethasone administration In Orth s review of 630 cases of Cushing syndrome of endogenous cause, 65 percent were due to hyperpituitarism (Cushing disease), 12 percent to an ectopic production of ACTH, 10 percent to an adrenal adenoma, and 8 percent to adrenal carcinoma.

Graphs of y = 5x3 + 3x2 + 5x + 7 and y = 2x3 + x2 + 2x + 5. The first function is graphed as a solid curve; the second function is graphed as a dashed curve. The realnumber solution appears as the point where the curves intersect. On the x axis, each increment is 1/2 unit. On the y axis, each increment is 10 units.

In Cushing disease, hyperplasia of pituitary cells or a betterde ned basophil or chromophobe adenoma produce ACTH, which stimulates the adrenals Unlike the usual pituitary tumors, the corticotroph (basophil) type are usually microadenomas ( 1 cm) and enlarge the sella in only 20 percent of cases However, it is now appreciated by MRI or high-resolution CT through the sella, that either micro- or macroadenomas are the cause in about 80 percent of cases There are only a few cases in which a hypothalamic tumor such as a gangliocytoma has caused Cushing syndrome For diagnostic purposes, measurement of the excretion of cortisol over 24 h in the urine is the most expeditious test and superior to serum sampling because of uctuations in the serum levels of ACTH.

If a 24-h urine collection is not feasible, it is advisable to obtain two or three daily determinations, since the values may vary from day to day in Cushing syndrome and patients are frequently unable to save all their urine The normal value for urinary excretion of cortisol is approximately 12 to 40 mg in 24 h, but some assays that measure additional metabolites of the hormone may allow normal values up to 100 mg This should be followed by low- or high-dose dexamethasone suppression testing A test using high doses of dexamethasone (2 mg every 6 h orally for 2 days, or a single dose of 8 mg at midnight) is the most dependable screening method for separating Cushing disease from ectopic secretion of ACTH.

Ratio spreads are an evolution of the bull call or bear put spread. They combine long purchased options with multiple short options. Ratio spreads bring an additional short option premium to purchased options to reduce the premium outlay, protect against time value decay, and insulate long options from signi cant reductions in implied volatility. For an example of a ratio spread we will look again at Caterpillar, Inc. (CAT) options with a few more out-of-the-money options selected on both calls and puts. We are using CAT again because of the in ated implied volatility on the out-of-the-money call options.

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